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Clinical Hematology and Fundamentals of Hemostasis, Fifth Edition

Denise M. Harmening, Ph.D MT(ASCP), CLS(NCA)

ISBN-13: 978-0-8036-1732-2
ISBN-10: 0-8036-1732-1

1,003 pp. 600 ill. Hard cover.
©2009 Available now.
List Price $124.00 - Special Student Price $91.00 plus shipping

Professors: If you have adopted this book, you may obtain the accompanying materials by filling out this FORM.

Two Free videos (of your choice) for Class Adoptions* when purchased from this website:

  • Solubility Testing      ISBN: 978-0-943903-16-3
  • Reticulocyte Count Procedure     ISBN: 978-0-943903-17-0
  • Preparing and Loading the Hemocytometer      ISBN: 978-0-943903-15-6
  • Erythrocyte Sedimentation Rate     ISBN: 978-0-943903-14-9
  • Peripheral Blood Smear      ISBN: 978-0-943903-13-2

Instructor Resources:

Free Student Resources:

The Fifth Edition of Clinical Hematology and Fundamentals of Hemostasis, is three books for the price of one—a text, a laboratory procedures manual, and an atlas of cell morphology—all in full color! The tools your students need to quickly master the basic principles of hematology and the fundamentals of hemostasis are here. They’ll begin with an introduction to clinical hematology and the anemias, and then progress through white blood cell disorders, and hemostasis to thrombosis, and laboratory methods.


  • Complete coverage of red blood cells, white blood cells, hemostasis, and thrombosis
  • Chapters on flow cytometry and molecular diagnosis
  • Thorough discussion of anemias
  • Case histories demonstrate the link between the test and the patient to foster critical thinking
  • Laboratory methods section includes chapters on routine hematology methods, automated differential analysis, cytochemistry, and more
  • More than 900 illustrations, including 309 full-color microphotographs
  • Chapter Outline and Educational Objectives at the beginning of each chapter
  • Study Questions and answers for each chapter
  • Table of normal hematologic values on the inside covers
  • Glossary for easy access to definitions for medical terms unique to hematology and hemostasis
  • Summary charts provide quick review, enhancing readability

Table of Contents

I. Introduction to Clinical Hematology

  • 1. Morphology of Human Blood and Marrow Cells: Hematopoiesis
  • 2. Bone Marrow
  • 3. The Red Blood Cell: Structure and Function
  • 4. Anemia: Diagnosis and Clinical Considerations
  • 5. Evaluation of Cell Morphology and Introduction to Platelet and White Cell Morphology

II. Anemias

  • 6. Iron Metabolism and Hypochromic Anemias
  • 7. Megaloblastic Anemias
  • 8. Aplastic Anemia Including Pure Red Cell Aplasia and Congenital Dyserythropoietic Anemia and Paroxysmal Noctural Hemoglobinuria (PNH)
  • 9. Introduction to Hemolytic Anemias: Intracorpuscular Defects: I. Hereditary Defects of the Red Cell Membrane
  • 10. Hemolytic Anemias: Intracorpuscular Defects: II. Hereditary Enzyme Deficiencies
  • 11. Hemolytic Anemias: Intracorpuscular Defects: III. The Hemoglobinopathies
  • 12. Hemolytic Anemias: Intracorpuscular Defects: IV. Thalassemia
  • 13. Hemolytic Anemias: Extracorpuscular Defects
  • 14. Hypoproliferative Anemia: Anemia Associated with Systemic Diseases

III. White Blood Cell Disorders

  • 15. Cell Biology, Disorders of Neutrophils, Infectious Mononucleosis, and Reactive Lymphocytosis
  • 16. Introduction to Leukemia and the Acute Leukemias
  • 17. Chronic Myeloproliferative Disorders: I. Chronic Myclogenous Leukemia
  • 18. Chronic Myeloproliferative Disorders: II. Polycythemia Vera, Essential Thrombocythemia, and Idiopathic Myelofibrosis
  • 19. Myelodysplastic Syndromes (MDS)
  • 20. chronic Lymphocytic Leukemia and Related Lymphoproliferative Disorders
  • 21. The Lymphomas
  • 22. Multiple Myeloma and Related Plasma Cell Disorders
  • 23. Lipid (Lysosomal) Storage Diseases and Histiocytosis

IV. Hemostasis and Introduction to Thrombosis

  • 24. Introduction to Hemostasis
  • 25. Disorders of Primary Hemostasis: Quantitative and Qualitative Platelet Disorders and Vascular Disorders
  • 26. Disorders of Plasma Clotting Factors
  • 27. Interaction of the Fibrinolytic, Coagulation, and Kinin Systems: Disseminated Intravascular Coagulation; and Related Pathology
  • 28. Introduction to Thrombosis and Anticoagulant Therapy

V. Laboratory Methods

  • 29. Quality Control in the Hematology Laboratory
  • 30. Body Fluid Examination: The Qualitative, Quantitative, and Morphologic Analysis of Serous, Cerebrospinal, and Synovial Fluids
  • 31. Hematology Methods
  • 32. Principles of Automated Differential Analysis
  • 33. Coagulation Procedures
  • 34. Applications of Flow Cytometry to Hematology and Hemostasis
  • 35. Molecular Diagnostic Techniques in Hematopathology
  • 36. Special Stains/Cytochemistry

* - A Class consists of a minimum of 10 students, each with their own book.

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